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## Details
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`gcnvplot` uses a median-of-ratios normalization. For `create-background`, let `c_ij` be the raw count for interval `i` in background sample `j`.
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The `gcnvplot` tool uses a median-of-ratios normalization. For `create-background`, let `c_ij` be the raw count for interval `i` in background sample `j`.
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1. Interval baseline:
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`upper_i = log2((p95_i + 0.01) / (m_i + 0.01))`
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This means the plotted curve shows relative dosage after library-size normalization, while the ribbon shows where the central background cohort typically lies for each interval.
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This means the plotted curve shows relative signal after size normalization, while the ribbon shows where the central background cohort typically lies for each interval.

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