Predicting human pharmacokinetic parameters of drugs using a multi-tissue chip platform integrating liver, kidney, and skeletal muscle microphysiological systems #18
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Journal publications table
Year|Title|URL|Source|DOI
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2026|<a href="https://github.com/Open-Systems-Pharmacology/OSP-based-publications-and-content/issues/740">Predicting human pharmacokinetic parameters of drugs using a multi-tissue chip platform integrating liver, kidney, and skeletal muscle microphysiological systems</a>|<a href="https://pubmed.ncbi.nlm.nih.gov/42047333/">https://pubmed.ncbi.nlm.nih.gov/42047333/</a>|Lab Chip. 2026 May 20;26(10):3054-3068.|<a href="https://doi.org/10.1039/d6lc00008h">10.1039/d6lc00008h</a>
2026|<a href="https://github.com/Open-Systems-Pharmacology/OSP-based-publications-and-content/issues/739">Advances in artificial intelligence for predictive toxicology: From QSAR and omics integration to clinical safety translation</a>|<a href="https://pubmed.ncbi.nlm.nih.gov/42142468/">https://pubmed.ncbi.nlm.nih.gov/42142468/</a>|Comput Biol Chem. 2026 May 10;124(Pt 1):109120|<a href="https://doi.org/10.1016/j.compbiolchem.2026.109120">10.1016/j.compbiolchem.2026.109120</a>
2026|<a href="https://github.com/Open-Systems-Pharmacology/OSP-based-publications-and-content/issues/738">Physiologically-based pharmacokinetic modeling of belimumab for systemic lupus erythematosus patients to predict the withdrawal time in pregnancy and vaccine time in infants</a>|<a href="https://pubmed.ncbi.nlm.nih.gov/42086179/">https://pubmed.ncbi.nlm.nih.gov/42086179/</a>|Eur J Pharm Sci. 2026 Jul 1:222:107545.|<a href="https://doi.org/10.1016/j.ejps.2026.107545">10.1016/j.ejps.2026.107545</a>
2026|<a href="https://github.com/Open-Systems-Pharmacology/OSP-based-publications-and-content/issues/736">Physiologically Based Pharmacokinetic Modeling and Pharmacodynamic Target Attainment Analysis for Ceftriaxone Dosing in Pregnant Women: Model Development and Clinical Applications</a>|<a href="https://pubmed.ncbi.nlm.nih.gov/42130310/">https://pubmed.ncbi.nlm.nih.gov/42130310/</a>|J Clin Pharmacol. 2026 May;66(5):e70205.|<a href="https://doi.org/10.1002/jcph.70205">10.1002/jcph.70205</a>
2026|<a href="https://github.com/Open-Systems-Pharmacology/OSP-based-publications-and-content/issues/734">A unified physiologically based pharmacokinetic model for low-to-high oral, subcutaneous, and intravenous dose of methotrexate in humans</a>|<a href="https://pubmed.ncbi.nlm.nih.gov/42235850/">https://pubmed.ncbi.nlm.nih.gov/42235850/</a>|J Pharm Sci. 2026 Jun 2;115(8):104348.|<a href="https://doi.org/10.1016/j.xphs.2026.104348">10.1016/j.xphs.2026.104348</a>
2026|<a href="https://github.com/Open-Systems-Pharmacology/OSP-based-publications-and-content/issues/733">Model-informed safety management of tocilizumab for pediatric sJIA: a PBPK approach for dose-escalation and vaccination timing</a>|<a href="https://pubmed.ncbi.nlm.nih.gov/42305545/">https://pubmed.ncbi.nlm.nih.gov/42305545/</a>|Front Immunol. 2026 Jun 1:17:1847997.|<a href="https://doi.org/10.3389/fimmu.2026.1847997">10.3389/fimmu.2026.1847997</a>
2026|<a href="https://github.com/Open-Systems-Pharmacology/OSP-based-publications-and-content/issues/731">Integrating In-vitro Permeability Assays within PBPK Modeling to Predict CNS Distribution of Standard and Engineered Antibodies</a>|<a href="https://pubmed.ncbi.nlm.nih.gov/41998432/">https://pubmed.ncbi.nlm.nih.gov/41998432/</a>|AAPS J. 2026 Apr 18;28(3):90.|<a href="https://doi.org/10.1208/s12248-026-01233-y">10.1208/s12248-026-01233-y</a>
2026|<a href="https://github.com/Open-Systems-Pharmacology/OSP-based-publications-and-content/issues/730">Open Systems Pharmacology Community Conference (OSP-CC) Proceedings 2025</a>|<a href="https://pubmed.ncbi.nlm.nih.gov/41721751/">https://pubmed.ncbi.nlm.nih.gov/41721751/</a>|CPT Pharmacometrics Syst Pharmacol. 2026 Mar;15(3):e70217.|<a href="https://doi.org/10.1002/psp4.70217">10.1002/psp4.70217</a>
2026|<a href="https://github.com/Open-Systems-Pharmacology/OSP-based-publications-and-content/issues/729">Comprehensive Pathophysiology Repository for PBPK Modeling in Liver Cirrhosis: Quantifying Continuous Disease Progression and Population Variability</a>|<a href="https://ascpt.onlinelibrary.wiley.com/doi/10.10
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