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fixing language#168

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zelixir25 wants to merge 2 commits into
TripSit:mainfrom
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Open

fixing language#168
zelixir25 wants to merge 2 commits into
TripSit:mainfrom
zelixir25:main

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@zelixir25

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updated language for cns depressant combos hopefully did it right this time fingers crossed lol

updated notes for depressant combos to emphasize the risk of resp depression + death
fixing a whoopsie
@zelixir25 zelixir25 requested a review from utaninja as a code owner March 1, 2025 15:49
Comment thread combos.json
"status": "Unsafe"
},
"tramadol": {
"note": "Increased risk of serotonin syndrome.",

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Spies, P. E., Pot, J. L. W. H., Willems, R. P. J., Bos, J. M., & Kramers, C. (2017). Interaction between tramadol and selective serotonin reuptake inhibitors: are doctors aware of potential risks in their prescription practice?. European journal of hospital pharmacy : science and practice, 24(2), 124–127. https://doi.org/10.1136/ejhpharm-2015-000838
Park SH, Wackernah RC, Stimmel GL. Serotonin Syndrome: Is It a Reason to Avoid the Use of Tramadol With Antidepressants? Journal of Pharmacy Practice. 2013;27(1):71-78. doi:10.1177/0897190013504957

The second study noted dosage is relevant, perhaps we can reword to note this. (ie medical dosages may not be of concern with monitoring, but higher/recreational doses are of higher risk)

Comment thread combos.json

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While unconscious, may cause vomit aspiration as well.

I like the overall wording changes but this sentence seems a bit odd to me. Could we reword it?

"Both drugs increase the CNS depressant effects of each other. There is a high risk of blackouts/memory loss, unconsciousness, and respiratory depression leading to death. While unconscious, there is a risk of dangerous vomit aspiration as well."

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Added comments within the file :)
Two small changes requested/noted

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5 participants