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CIRCexplorer2

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CIRCexplorer2 is the successor of CIRCexplorer with plenty of new features to facilitate circular RNA identification and characterization.

Features

  • Precisely annotate circular RNAs with high accuracy, good sensitivity and low memory consumption
  • Support multiple circular RNA aligners (TopHat2/TopHat-Fusion, STAR, MapSplice, BWA and segemehl)
  • De novo assemble novel circular RNA transcripts
  • Characterize various of alternative splicing events of circular RNAs
  • Fast identify circuar RNAs with STAR or BWA
  • Support both single-read and paired-end sequencing.

CIRCexplorer2 documentation is available through https://readthedocs.org/ from here, including installation instructions and tutorial.

Citation

Zhang XO*, Dong R*, Zhang Y*, Zhang JL, Luo Z, Zhang J, Chen LL#, Yang L#. Diverse alternative back-splicing and alternative splicing landscape of circular RNAs. Genome Res, 2016, 26:1277-1287