@@ -8,7 +8,7 @@ This is the user's manual for cosi2 coalescent simulator.
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99* Downloading and installing cosi2
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11- cosi2 can be downloaded from http ://broadinstitute.org/mpg /cosi2 .
11+ cosi2 can be downloaded from https ://github.com/broadinstitute /cosi2 .
1212
1313Quick start instructions:
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@@ -185,6 +185,8 @@ simulated. The -m option requests output to be written to stdout in the format o
185185 -p [ --paramfile ] arg parameter file
186186 -R [ --recombfile ] arg genetic map file (if specified, overrides the
187187 one in paramfile)
188+ --genmapRandomRegions for each simulation use a randomly chosen
189+ subregion of the genetic map
188190 -n [ --nsims ] arg (=1) number of simulations to output
189191 -r [ --seed ] arg (=0) random seed (0 to use current time)
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@@ -203,6 +205,8 @@ simulated. The -m option requests output to be written to stdout in the format o
203205 Specifying the output format:
204206 -o [ --outfilebase ] arg base name for output files in cosi format
205207 -m [ --outms ] write output to stdout in ms format
208+ --tped write output to stdout in tped format
209+ (alleles: 1=ancestra, 0=derived)
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207211 Specifying output details:
208212 -P [ --output-precision ] arg number of decimal places used for floats in the
@@ -211,6 +215,8 @@ simulated. The -m option requests output to be written to stdout in the format o
211215 -L [ --write-recomb-locs ] output recombination locations
212216
213217 Misc options:
218+ -r N specify random seed N
219+ --nTriesPerSim number of times to try each simulation
214220 -h [ --help ] produce help message
215221 -V [ --version ] print version info and compile-time
216222 options
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