📢 New social post: LLM agents reanalyze RNA-seq (galaxyproject.org news)

Co-Authored-By: Claude Fable 5 <noreply@anthropic.com>

Author: nekrut

posts/2026/2026-06-09-llm-agents-rnaseq.md

@@ -0,0 +1,56 @@
+---
+media:
+  - mastodon-galaxyproject
+  - bluesky-galaxyproject
+  - linkedin-galaxyproject
+  - mastodon-brc
+  - bluesky-brc
+  - linkedin-brc
+hashtags:
+  mastodon-galaxyproject:
+  - UseGalaxy
+  - RNAseq
+  - AI
+  - LLM
+  - Bioinformatics
+  bluesky-galaxyproject:
+  - UseGalaxy
+  - RNAseq
+  - AI
+  - LLM
+  - Bioinformatics
+  linkedin-galaxyproject:
+  - UseGalaxy
+  - RNAseq
+  - AI
+  - LLM
+  - Bioinformatics
+  mastodon-brc:
+  - UseGalaxy
+  - RNAseq
+  - AI
+  - LLM
+  - Bioinformatics
+  bluesky-brc:
+  - UseGalaxy
+  - RNAseq
+  - AI
+  - LLM
+  - Bioinformatics
+  linkedin-brc:
+  - UseGalaxy
+  - RNAseq
+  - AI
+  - LLM
+  - Bioinformatics
+images:
+  - url: https://galaxyproject.org/images/news/2026-06-09-llm-agents-reanalyze-rnaseq/scf1-across-attempts.png
+    alt_text: "SCF1 expression across eight LLM agent attempts to reproduce a Candida auris RNA-seq analysis in Galaxy."
+  - url: https://raw.githubusercontent.com/nekrut/galaxy-social/6876fd622c58a369f06b48500472e05298c7e984/posts/images/2026-06-09-llm-cost-spread.png
+    alt_text: "Panel B: lollipop chart of LLM API cost per completing run, spanning ~47x from DeepSeek ($2.82) to Opus ($131.83), while all reach the same answer."
+---
+Eight frontier LLMs, one RNA-seq dataset. We had them reproduce a published *Candida auris* analysis by driving Galaxy through its Orbit interface.
+
+Six models independently replicated the original SCF1 downregulation finding—while their API costs varied 47× ($2.82–$131.83).
+
+Agentic bioinformatics is genuinely promising, with plenty of room for better tooling. Read what we learned: https://galaxyproject.org/news/2026-06-09-llm-agents-reanalyze-rnaseq/