Add Folklore variant evidence skill - #232
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Summary
Adds a focused Agent Skill for retrieving and reviewing source-linked public
variant evidence and literature through Folklore Clinical Variant Interpretation
MCP, published by Helena Bioinformatics.
The skill is intentionally distinct from the existing
database-lookupandgenomic-coordinatesskills. It covers one public GRCh38 germline SNV or simpleindel through a structured live evidence contract, preserves six explicit
resolution states, stops on ambiguity, and chains only resolved variants into
source-linked literature review.
Type of change
Skills touched
folklore-variant-evidenceHow this was tested
The public endpoint was also checked directly:
tools/listreturnedsearch_variant_evidence,search_variant_literature,get_publication_details, andsearch_literature_corpus.rs80357914smoke test returnedambiguouswith twocandidates, confirming the skill's stop-and-select control flow.
was verified by POST using the documented public protocol contract.
Related issues and references
https://github.com/helena-bioinformatics/folklore-mcp
io.github.helena-bioinformatics/folkloreChecklist
Skill format
namefrontmatter match exactly.SKILL.mdandreferences/.SKILL.mdhas valid YAML frontmatter and a Markdown body.metadatais a block mapping and scalar values are quoted where needed.metadata.openclawormetadata.hermesblock is used.metadata.versionexists and is quoted.Validation and tests
skills-ref validatepasses.are not required.
Content and safety
included.
Notes for reviewers
Folklore Clinical Variant Interpretation MCP accepts public variant-level
queries only. It does not accept patient, phenotype, family, segregation, or
private case data. Results require qualified professional review and are not a
diagnosis or treatment recommendation. The skill explicitly directs broad
direct-database lookup and coordinate normalization tasks to the repository's
existing skills to avoid duplicating their scope.