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17 changes: 9 additions & 8 deletions README.md
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# Claude Scientific Skills

[![License: MIT](https://img.shields.io/badge/License-MIT-yellow.svg)](LICENSE.md)
[![Skills](https://img.shields.io/badge/Skills-148-brightgreen.svg)](#whats-included)
[![Skills](https://img.shields.io/badge/Skills-149-brightgreen.svg)](#whats-included)
[![Databases](https://img.shields.io/badge/Databases-250%2B-orange.svg)](#whats-included)
[![Agent Skills](https://img.shields.io/badge/Standard-Agent_Skills-blueviolet.svg)](https://agentskills.io/)
[![Works with](https://img.shields.io/badge/Works_with-Cursor_|_Claude_Code_|_Codex-blue.svg)](#getting-started)

A comprehensive collection of **148+ ready-to-use scientific and research skills** (now including financial/SEC research, U.S. Treasury fiscal data, OFR Hedge Fund Monitor, and Alpha Vantage market data) for any AI agent that supports the open [Agent Skills](https://agentskills.io/) standard, created by [K-Dense](https://k-dense.ai). Works with **Cursor, Claude Code, Codex, and more**. Transform your AI agent into a research assistant capable of executing complex multi-step scientific workflows across biology, chemistry, medicine, and beyond.
A comprehensive collection of **149+ ready-to-use scientific and research skills** (now including financial/SEC research, U.S. Treasury fiscal data, OFR Hedge Fund Monitor, and Alpha Vantage market data) for any AI agent that supports the open [Agent Skills](https://agentskills.io/) standard, created by [K-Dense](https://k-dense.ai). Works with **Cursor, Claude Code, Codex, and more**. Transform your AI agent into a research assistant capable of executing complex multi-step scientific workflows across biology, chemistry, medicine, and beyond.

<p align="center">
<a href="https://k-dense.ai">
Expand All @@ -30,6 +30,7 @@ These skills enable your AI agent to seamlessly work with specialized scientific
- 🌌 Physics & Astronomy - Astronomical data analysis, coordinate transformations, cosmological calculations, symbolic mathematics, physics computations
- ⚙️ Engineering & Simulation - Discrete-event simulation, multi-objective optimization, metabolic engineering, systems modeling, process optimization
- 📊 Data Analysis & Visualization - Statistical analysis, network analysis, time series, publication-quality figures, large-scale data processing, EDA
- 🌍 Geospatial Science & Remote Sensing - Satellite imagery processing, GIS analysis, spatial statistics, terrain analysis, machine learning for Earth observation
- 🧪 Laboratory Automation - Liquid handling protocols, lab equipment control, workflow automation, LIMS integration
- 📚 Scientific Communication - Literature review, peer review, scientific writing, document processing, posters, slides, schematics, citation management
- 🔬 Multi-omics & Systems Biology - Multi-modal data integration, pathway analysis, network biology, systems-level insights
Expand All @@ -46,7 +47,7 @@ These skills enable your AI agent to seamlessly work with specialized scientific

## 📦 What's Included

This repository provides **148 scientific and research skills** organized into the following categories:
This repository provides **149 scientific and research skills** organized into the following categories:

- **250+ Scientific & Financial Databases** - Collectively, these skills provide access to over 250 databases and data sources. Dedicated skills cover PubMed, ChEMBL, UniProt, COSMIC, ClinicalTrials.gov, SEC EDGAR, Alpha Vantage, and more; multi-database packages like BioServices (~40 bioinformatics services + 30+ PSICQUIC interaction databases), BioPython (38 NCBI sub-databases via Entrez), and gget (20+ genomics databases) account for the rest
- **55+ Optimized Python Package Skills** - Explicitly defined skills for RDKit, Scanpy, PyTorch Lightning, scikit-learn, BioPython, pyzotero, BioServices, PennyLane, Qiskit, and others — with curated documentation, examples, and best practices. Note: the agent can write code using *any* Python package, not just these; these skills simply provide stronger, more reliable performance for the packages listed
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- **Multi-Step Workflows** - Execute complex pipelines with a single prompt

### 🎯 **Comprehensive Coverage**
- **148 Skills** - Extensive coverage across all major scientific domains
- **149 Skills** - Extensive coverage across all major scientific domains
- **250+ Databases** - Collective access to 250+ databases and data sources spanning genomics, chemistry, clinical, financial, and more — through dedicated database skills and multi-database packages like BioServices, BioPython, and gget
- **55+ Optimized Python Package Skills** - RDKit, Scanpy, PyTorch Lightning, scikit-learn, BioServices, PennyLane, Qiskit, and others (the agent can use any Python package; these are the pre-documented, higher-performing paths)

Expand Down Expand Up @@ -331,7 +332,7 @@ If so, **[K-Dense Web](https://k-dense.ai)** was built for you. It is the full A

| Feature | This Repo | K-Dense Web |
|---------|-----------|-------------|
| Scientific Skills | 148 skills | **200+ skills** (exclusive access) |
| Scientific Skills | 149 skills | **200+ skills** (exclusive access) |
| Setup | Manual installation | **Zero setup, works instantly** |
| Compute | Your machine | **Cloud GPUs and HPC included** |
| Workflows | Prompt and code | **End-to-end research pipelines** |
Expand Down Expand Up @@ -394,7 +395,7 @@ If so, **[K-Dense Web](https://k-dense.ai)** was built for you. It is the full A

## 📚 Available Skills

This repository contains **148 scientific and research skills** organized across multiple domains. Each skill provides comprehensive documentation, code examples, and best practices for working with scientific libraries, databases, and tools.
This repository contains **149 scientific and research skills** organized across multiple domains. Each skill provides comprehensive documentation, code examples, and best practices for working with scientific libraries, databases, and tools.

### Skill Categories

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- Discrete-event simulation: SimPy
- Data processing: Dask, Polars, Vaex

#### 📊 **Data Analysis & Visualization** (14+ skills)
#### 📊 **Data Analysis & Visualization** (15+ skills)
- Visualization: Matplotlib, Seaborn, Plotly, Scientific Visualization
- Geospatial analysis: GeoPandas
- Geospatial analysis: GeoPandas, GeoMaster (comprehensive geospatial science covering remote sensing, GIS, spatial analysis, satellite imagery processing, machine learning for Earth observation, 8 programming languages, cloud-native workflows with STAC/COG, and comprehensive troubleshooting guide)
- Network analysis: NetworkX
- Symbolic math: SymPy
- Document processing: Document Skills (PDF, DOCX, PPTX, XLSX)
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