First Release

ITDiscover v0.1.0

First functional release of ITDiscover for calling internal tandem duplications (ITDs) from amplicon sequencing data.

Added

• Exact-match calling from paired-end FASTQ input
• Flat CLI interface:
  • itdiscover --reference ... --r1 ... --r2 ...
• Call-level reporting of:
  • tandem start
  • insertion start
  • duplicated sequence
  • support count
  • unique support count
  • coverage
  • VAF
• HTML support report via --output report.html
• Representative-alignment reporting for unique support patterns
• Per-pattern support counts in the HTML report
• Base-level highlighting of differences between support representatives

Known limitations

• Exact-match ITD detection only in this release
• No fuzzy similarity-based ITD classification yet
• No extended annotation layer yet beyond current call/report output