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This repository was archived by the owner on Jan 26, 2026. It is now read-only.

First version of circtools released [1.0.0]

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@tjakobi tjakobi released this 28 Jun 14:28

We are proud to release the first version of circtools, version 1.0.0 as of today.

The 0.1 branch contains the following modules:

detect

The detect command is an interface to DCC, also developed at the Dieterich lab. DCC is a circular RNA detection tool based on STAR alignment files.

reconstruct

The reconstruct command is an interface to FUCHS. FUCHS is employing DCC-generated data to reconstruct circRNA structures.

primer

The primer command is used to design and visualize primers required for follow up wet lab experiments to verify circRNA candidates.

enrich

The enrichment module may be used to identify circRNAs enriched for specific RNA binding proteins (RBP) based on DCC-identified circRNAs and processed eCLIP data. For K526 and HepG2 cell lines plenty of this data is available through the ENCODE project.

Having issues?

Please be so kind and top us a message via the issue form. We appreciate your feedback and will do what we can to assist you in using circtools.