First version of circtools released [1.0.0]
We are proud to release the first version of circtools, version 1.0.0 as of today.
The 0.1 branch contains the following modules:
detect
The detect command is an interface to DCC, also developed at the Dieterich lab. DCC is a circular RNA detection tool based on STAR alignment files.
reconstruct
The reconstruct command is an interface to FUCHS. FUCHS is employing DCC-generated data to reconstruct circRNA structures.
primer
The primer command is used to design and visualize primers required for follow up wet lab experiments to verify circRNA candidates.
enrich
The enrichment module may be used to identify circRNAs enriched for specific RNA binding proteins (RBP) based on DCC-identified circRNAs and processed eCLIP data. For K526 and HepG2 cell lines plenty of this data is available through the ENCODE project.
Having issues?
Please be so kind and top us a message via the issue form. We appreciate your feedback and will do what we can to assist you in using circtools.