hello, i appreciate the logic for not reporting any mutations with supporting reads in bulk WGS, but this probably is redundant if there is matched high coverage bulk genome eg 100x WGS- even low clonal mutations might have supporting reads. Could there be an option to report separately the single cell putative sSNVs with a low number of matching bulk reads, (to be set manually)? Thanks
hello, i appreciate the logic for not reporting any mutations with supporting reads in bulk WGS, but this probably is redundant if there is matched high coverage bulk genome eg 100x WGS- even low clonal mutations might have supporting reads. Could there be an option to report separately the single cell putative sSNVs with a low number of matching bulk reads, (to be set manually)? Thanks