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30 changes: 30 additions & 0 deletions posts/2026/retry-697_2026-06-09-llm-agents-rnaseq.md
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---
media:
- linkedin-brc
- linkedin-galaxyproject
hashtags:
linkedin-galaxyproject:
- UseGalaxy
- RNAseq
- AI
- LLM
- Bioinformatics
linkedin-brc:
- UseGalaxy
- RNAseq
- AI
- LLM
- Bioinformatics
images:
- url: https://galaxyproject.org/images/news/2026-06-09-llm-agents-reanalyze-rnaseq/scf1-across-attempts.png
alt_text: SCF1 expression across eight LLM agent attempts to reproduce a Candida
auris RNA-seq analysis in Galaxy.
- url: https://raw.githubusercontent.com/nekrut/galaxy-social/6876fd622c58a369f06b48500472e05298c7e984/posts/images/2026-06-09-llm-cost-spread.png
alt_text: 'Panel B: lollipop chart of LLM API cost per completing run, spanning
~47x from DeepSeek ($2.82) to Opus ($131.83), while all reach the same answer.'
---
Eight frontier LLMs, one RNA-seq dataset. We had them reproduce a published *Candida auris* analysis by using Orbit to drive Galaxy.

Six models independently replicated the original *SCF1* downregulation finding—while their API costs varied 47× ($2.82–$131.83).

Read what we learned: https://galaxyproject.org/news/2026-06-09-llm-agents-reanalyze-rnaseq/
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