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THRESHER

THRESHER is a framework that replaces fixed cutoffs with data-driven phylothresholds, the SNP thresholds corrected for phylogenetic topology and inferred directly from each dataset's genomic structure.

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Graphical Workflow

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Advanced Usage

Development Status

Please be advised that this pipeline is still in its early development stage. It is subject to significant changes in terms of options, outputs, and other functionalities. Users should be prepared for potential modifications and updates in future releases.

Authors

Qianxuan (Sean) She

Acknowledgments

Developed under the mentorship of:

Dr. Paul J. Planet
Email: planetp@chop.edu

Dr. Ahmed M. Moustafa
Email: moustafaam@chop.edu

Dr. Joseph P. Zackular
Email: joseph.zackular@pennmedicine.upenn.edu

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THRESHER is a framework that replaces fixed cutoffs with data-driven phylothresholds - the SNP thresholds corrected for phylogenetic topology and inferred directly from each dataset's genomic structure.

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